Botox vs. Dysport vs. Jeuveau: Your Complete Guide to Neuromodulators

Are you seeking a solution to crow’s feet, frown lines, or forehead lines? Maybe you’ve heard of Botox, Dysport, or Jeuveau, but aren’t sure which is right for you. These FDA-approved neurotoxins can address a variety of cosmetic concerns, such as fine lines and wrinkles, but each has unique characteristics that might make one a better fit for you than the others. 

In this comprehensive guide, we’ll break down the differences between these popular neuromodulators to help you make an informed decision.

Neurotoxins 101

Neurotoxins are a type of protein that targets the nervous system, disrupting the signaling processes that allow neurons to communicate. In the context of dermatology and cosmetic use, injections containing the botulinum toxin are administered in small, safe doses to selectively and temporarily weaken specific muscles. This ability to precisely target muscle activity has revolutionized the field of cosmetic dermatology.

Botulinum toxin injections prevent the targeted facial muscles from contracting fully, leading to a softening and smoothing of the overlying skin. The result is a reduction in the appearance of wrinkles and fine lines caused by repetitive facial expressions, such as frown lines, forehead lines, and crow’s feet. 

The effects are temporary, typically lasting anywhere from three to six months. This means treatments can be adjusted and refined over time to suit the evolving needs and preferences of each patient. 

Botox Cosmetic: The Original Neuromodulator

Botox Cosmetic (onabotulinumtoxinA) has been around the longest of these three treatments and is often the first name that comes to mind when thinking of neurotoxins. Developed by Allergan, Botox has a wide range of both cosmetic and medical applications. 

Botox works by blocking nerve signals in the muscles where it is injected, leading to temporary muscle paralysis. This reduces the facial expressions that contribute to fine lines and wrinkles, providing a smoother and more youthful appearance. Botox is most commonly used for frown lines, crow’s feet, forehead lines, and glabellar lines (vertical lines between the eyebrows), but it’s also FDA-approved to treat medical conditions such as migraines, temporomandibular joint (TMJ) pain, and excessive sweating.

The effects of Botox injections usually start to appear within a few days of treatment and last anywhere from three to six months, depending on the individual and the treatment area. After the effects wear off, additional appointments can maintain the results.

Dysport: Quick Diffusion and Natural Results

Like Botox, Dysport (abobotulinumtoxinA) is a type A botulinum toxin that provides temporary paralysis of the muscles injected, softening the appearance of wrinkles. However, Dysport has a different protein formulation than Botox, which leads to quicker diffusion in the injection area.

Dysport injections spread more than Botox, which can be advantageous for treating larger areas such as extensive forehead lines. The diffusion can lead to a more natural look, less “frozen” than the results of some other neuromodulators. However, this spreading effect can be a downside if precise targeting is needed.

The onset of Dysport’s effects is generally a bit quicker than Botox, often within 2-3 days, and the results last about the same amount of time: between three and six months.

Jeuveau: The New Kid on the Block

Jeuveau (prabotulinumtoxinA), also known as Newtox, is the newest neurotoxin to hit the market. Like Botox and Dysport, Jeuveau is used to temporarily improve the appearance of frown lines and wrinkles.

Jeuveau is structurally similar to Botox and works in much the same way. However, it’s processed differently during manufacturing, which some believe may contribute to better performance. Despite being the new kid on the block, clinical trials have shown Jeuveau to be just as effective as its counterparts.

Jeuveau injections start working within 2-3 days, and results last approximately three to six months, on par with both Botox and Dysport.

Choosing the Right Treatment for You

So, how do you decide between Botox, Dysport, and Jeuveau? The decision depends on various factors, such as the specific area being treated, your personal preferences, and your medical history. 

For instance, Botox might be the best choice for someone looking to address multiple concerns due to its wide range of FDA-approved uses. On the other hand, Dysport might be the best choice for someone looking for a softer, more natural result, especially in larger treatment areas. Finally, Jeuveau, with its unique manufacturing process, might be an excellent choice for those seeking the newest advances in neuromodulator technology.

Your injector’s expertise also plays a critical role in the outcome of the treatment. A board-certified dermatologist or plastic surgeon will be able to advise you on the best treatment for your goals and concerns. 

Remember that all three neurotoxins–Botox, Dysport, and Jeuveau–are very similar. They all contain the active ingredient botulinum toxin type A and work in the same basic way to relax muscles and reduce the appearance of wrinkles. The differences in protein formulations and processing methods can slightly affect the onset and duration of results, but in most cases, these differences are minor. It’s essential to discuss your expectations with your provider to choose the right treatment for you.

Side Effects and Safety Considerations

Neurotoxin injections are generally safe and effective when performed by a qualified provider. Common side effects are minor and temporary, including redness, swelling, or bruising at the injection site. However, more serious side effects can occur if the neurotoxin spreads beyond the treatment area, which is why choosing an experienced injector is crucial.

Keep in mind that neuromodulator injections are a medical procedure and not suitable for everyone. They should not be used in people who are allergic to any ingredient in the formulation or who have a skin infection at the proposed injection site. If you have any medical conditions, including plans for surgery, make sure to discuss this with your provider.

What’s It Like to Get Neurotoxin Injections?

Before you even feel the quick pinch of the injection, your journey begins with a thorough consultation. It’s here that you can discuss whether Botox, Dysport, or Jeuveau is right for you, as well as whether you’d like to incorporate other treatments, such as fillers, into your plan for a more comprehensive facial rejuvenation.

With a treatment plan in place, it’s time for the actual injection. The discomfort experienced is typically minor, often described as a quick pinch. To maximize your comfort, a topical numbing cream can be applied before the procedure. 

Recovery & aftercare

Once the injection process is complete, you should avoid rubbing or massaging the treated area for 24 hours to prevent the neurotoxin from migrating to unintended muscles. Other than that, most patients can return to their regular activities immediately post-treatment. 


While some effects of the neurotoxin might be noticeable within 2-3 days, the full effect is typically apparent after about two weeks. That’s when you’ll see a visible reduction in the appearance of wrinkles and lines, leading to a smoother, more youthful complexion.

Wrapping Up: The Right Neurotoxin for You

In conclusion, Botox, Dysport, and Jeuveau are all effective options for addressing fine lines and wrinkles, and each comes with its unique characteristics. A consultation with a board-certified provider at Lockhart Matter Dermatology in Prosper, TX, can help you understand which treatment is best suited to your individual needs and aesthetic goals. 

With extensive knowledge and experience in administering neurotoxin injections, our team can create a personalized treatment plan to help you achieve a refreshed and rejuvenated appearance. We are dedicated to providing the highest quality skin care, helping you feel confident in your skin. Contact us today to schedule your consultation.

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